The Latest Bad Rap on Supplements: What Does This Week’s Study Mean to Women?
Yesterday, I set out to write about the latest findings of a government-funded research study that concluded that in older women, several commonly used dietary vitamin and mineral supplements may do more harm than good; even, in some cases, causing a small increase in the risk of death.
Death? Really? From Vitamin B6 and multivitamins?
There must be more to this than was being reported, so I decided to go to the source, The Archives of Internal Medicine, where the findings were published, and read the study myself. Here’s what I learned.
First: The Facts
Researchers assessed the use of 15 vitamin and mineral supplements (including multivitamins, Vitamins B6, C and D, folic acid, magnesium, Iron and Calcium) in relation to total mortality in nearly 39,000 women in the Iowa Women’s Health Study. The participants were just under 62 years of age when they began the study in 1986. Supplement use, which was self-reported via a health questionnaire three times over 19 years, was widespread among these women and increased over the years.
In yesterday’s news reports about this study, we learned that the researchers found a small increase in the risk of death among older women who took dietary supplements compared with those who didn’t. However, what wasn’t reported in many news accounts was the fact that the women in the study who took supplements tended to be healthier, more physically active and had lower rates of diabetes and high blood pressure, with a lower BMI and waist-to-hip ratio than women who didn’t. Their diets were healthier too. Nevertheless, the women who took an iron supplement or multi-vitamin showed an increased risk for early death. Those who self-reported that they took Vitamin B complex, Calcium and Vitamins C, D, E had significantly lower risk of death compared with non use.
Over the 19 year period that these 39,000 women’s histories were tracked, about 16,000 – or 40 percent – died. Yet, the research did not explore whether supplements contributed to their deaths. That’s because they didn’t know why the women were taking the supplements in the first place.
Conclusions
So, can we conclude that vitamin and mineral supplements are a waste of money and even harmful. Does this study prove that the “try it, it can’t hurt,” attitude is old thinking?
The study’s first author, a researcher in nutrition at the University of Minnesota’s School of Public Health said, “this paper contributes to the growing amount of studies showing no benefits for supplement use in the prevention of chronic diseases. Millions of Americans take these, but there just don’t appear to be a lot of benefits.”
Bonnie Jortberg, a registered dietitian and senior instructor at the University of Colorado School of Medicine in Denver, said the research “bolstered arguments against using supplements other than in cases of known nutritional deficiency.”
Dr. David Heber, director of the UCLA Center for Human Nutrition, speaking to the L.A. Times said, “I wouldn’t recommend anyone change what they’re doing based on this study. It’s very hard to conclude cause and effect.”
The Alliance for Natural Health, a non-profit organization self-described as “committed to protecting access to integrative medicine,” called this study “junk science.” “To say the data is “unreliable” would be a generous description,” they wrote on their website yesterday. “In the study, all of the relative risks were so low as to be statistically insigificant. This kind of “data” has no place in a valid scientific study.”
IMHO, the findings of this study didn’t convince me that I should stop taking supplements. On the contrary, I feel better knowing that at least two of them, Vitamin D and Calcium, won’t likely be the cause of my death. Magnesium, which was among the 15 supplements assessed, has helped reduce the frequency of leg cramps that wake me up at night. So with a clear benefit for me, why should I stop taking this?
As with all studies, it makes you think about our own behaviors. With so much money being spent on supplements — $11.8 Billion just last year, according to the Nutrition Business Journal – maybe we should heed the advice of those scientists and medical professionals who say we should get all the nutrients we need from food whenever possible and only use supplements to correct diagnosed deficiencies.
What’s your take on this? Do you plan to cut back on the number of supplements you’re taking?
Related stories you might be interested in:
Use of Vitamins, Supplements Up
Vitamin Studies Spell Confusion for Patients
Do Vitamins Kill People? by Alan R. Gaby M.D.
You offer a lot of information about B6 on your website. But you don’t identify yourself or the reason for your interest. Can you shed some light on this?
Great article on the study of vitamins and mortality rates. I believe Vitamin B6 is one of the more important vitamins because it is involved in so many different enzymatic functions in the body. B6 is involved in the making of serotonin one of the the brains feel good chemicals. There are so many other benefits on vitamin b6 I could go on for ever.
HI Marian – I agree that this was a poor study and a weak conclusion. Unfortunately, it resulted in some sensational and misguiding.
Wow, they call this a study? I wonder whether the women taking the supplements had some health issues to begin with that lead them to take the supplements. Their conclusions are simply not supported. Besides that 23,000 were still alive and living beyond life expectancy. That’s 60% that are now 84 + years old. Maybe it’s the supplements!
Hi Joan – I don’t know if I sorted out the confusion – I continue to see stories about supplements causing death and I’ve received emails from readers expressing concern. I can only say for myself, I’m going to stick with the few supplements I’m taking. Sounds like you are too!
What a hot topic! Thanks for helping us sort out the confusion, Wendy. The reason I take a daily multi-vitamin is that according to nutritionists, we don’t absorb all the nutrients from food as we get older, even with a balanced diet. So after age 50, the daily multi acts to insure a full complement of nutritional values. I think I’ll stick with my One-a-Day. (And, like you, I take magnesium to prevent muscle cramps….and constipation).
Just like the Danish study in 2007 there are so many points that make this study not even plausible. The funny thing I mentioned in my blog post is have we ever seen any study that were publicized by the news that talk about the harmful effects of prescription drugs. Very few when they are hurting people every day.
Here is the blog post. It references the Orthomolecular rebutable which is very good.
Naturalhealth
Dr. Nunley, thanks for your comment and the link to the analysis by Dr. Verkerk. It not only sheds more light on this particular study, it also helps us learn how to parse and evaluate other studies that we read about almost every week.
Thanks for your comment, Jennifer. There seem to be many critical missing links in this study and unfortunately, only top-line information about the study’s findings were reported.
Hi Meaghan – You bring up a valid point, one of many criticisms of this study that has been pointed out. We don’t know if the supplements the study participants ingested were high quality, delivering the same consistent dosage in every bottle and if they even took them every day for nearly two decades. I find it hard to believe that this study was granted government funds to do this cohort study.
There are so many flaws in this study as to make it difficult to even call it a study. See this analysis by Dr Robert Verkerk,
http://www.anh-europe.org/news/anh-feature-iowa-women%E2%80%99s-health-study-do-supplements-kill-older-women-more-quickly
I would suggest that if we looked at prescription drug use in this way, it would be written off as ridiculous as there are so many other factors involved. Appropriately prescribed prescription drugs are the 3rd leading cause of death behind CV disease and all cancers combined. More people die from prescription drugs than from breast cancer every year. I don’t think this study contributes anything to the large body of literature that supports the use of supplements. We already know that iron, synthetic forms of vitamin E, folic acid and beta carotene can be detrimental. We can now measure for nutrient depletion and replace what is appropriate,
http://www.spectracell.com/, and we should check with a knowledgeable provider to make sure that the supplements we take are high grade with quality ingredients.
I for one will continue to take my supplements as I know they have contributed a great deal to my health and well being.
Excellent post.
I’m not sure what to make of the study but you make a really good point – we don’t know why women were taking supplements in the first place.
That’s a critical missing link, it seems to me.
Look forward to exploring your blog more!
Great blog with some really valid points. I wish this study also took into consideration the quality and consistency of the supplements being taken by these women. I am with you that I am not throwing away my supplements anytime soon. I feel much better since I have been on them.
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